INT270350

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.98
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (S1pr1) signal transducer activity (S1pr1)
Anatomy Link Frequency
platelets 2
S1pr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 6 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
substance P 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 2 288 94.28 High High
Hypoactive Sexual Desire Disorder 2 92.40 High High
Diabetes Mellitus 116 60.28 Quite High
Insulin Resistance 2 52.80 Quite High
Obesity 2 49.92 Quite Low
Metabolic Syndrome 6 48.84 Quite Low
Increased Venous Pressure Under Development 8 42.68 Quite Low
Coronary Artery Disease 30 16.72 Low Low
Necrosis 2 7.00 Low Low
Cancer 2 6.64 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sphingosine-1-phosphate (S1P) is a biologically active sphingolipid that is generated upon cell activation from membrane phospholipids as part of the sphingomyelin cycle.[5354] It is stored in red blood cells and in platelets.[55] S1P acts on five types of G-protein-coupled receptors termed S1P1-S1P5 (originally termed EDG (endothelial differentiation genes)).
Positive_regulation (generated) of S1P in platelets
1) Confidence 0.32 Published 2008 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2684375 Disease Relevance 0.49 Pain Relevance 0
Sphingosine-1-phosphate (S1P) is a biologically active sphingolipid that is generated upon cell activation from membrane phospholipids as part of the sphingomyelin cycle.[5354] It is stored in red blood cells and in platelets.[55] S1P acts on five types of G-protein-coupled receptors termed S1P1-S1P5 (originally termed EDG (endothelial differentiation genes)).
Positive_regulation (generated) of Sphingosine-1-phosphate in platelets
2) Confidence 0.28 Published 2008 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2684375 Disease Relevance 0.50 Pain Relevance 0

General Comments

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