INT270428

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Context Info
Confidence 0.41
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.16
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (APOE) aging (APOE) Golgi apparatus (APOE)
lipid metabolic process (APOE) cytoplasm (APOE) lipid binding (APOE)
APOE (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 8 96.96 Very High Very High Very High
aspirin 2 74.16 Quite High
diclofenac 1 72.36 Quite High
Inflammatory response 1 64.00 Quite High
Neuropeptide 1 56.16 Quite High
Inflammation 12 41.04 Quite Low
positron emission tomography 8 5.00 Very Low Very Low Very Low
Glutamate 7 5.00 Very Low Very Low Very Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
Somatostatin 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 125 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 4 100.00 Very High Very High Very High
Drug Induced Neurotoxicity 2 92.64 High High
INFLAMMATION 14 69.64 Quite High
Toxicity 23 50.16 Quite High
Apoptosis 4 47.16 Quite Low
Cognitive Disorder 28 41.76 Quite Low
Targeted Disruption 7 20.68 Low Low
Dementia 10 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a broad epidemiological study a reduction of the risk of AD in individuals with the Apo E-?
Negative_regulation (reduction) of Apo E Binding (individuals) of associated with disease
1) Confidence 0.41 Published 2009 Journal The Open Neurology Journal Section Body Doc Link PMC2684708 Disease Relevance 0.65 Pain Relevance 0.67
then it is also relevant that apolipoprotein E has been found to associate to
Negative_regulation (relevant) of apolipoprotein E Binding (found) of associated with disorder of lipid metabolism
2) Confidence 0.05 Published 2009 Journal Journal of Toxicology Section Body Doc Link PMC2809332 Disease Relevance 0.52 Pain Relevance 0.03

General Comments

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