INT270450

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.55
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptch1) extracellular region (Ptch1) plasma membrane (Ptch1)
Anatomy Link Frequency
cornea 2
Ptch1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 12 99.16 Very High Very High Very High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Wound Healing 4 98.88 Very High Very High Very High
Corneal Neovascularization 12 86.96 High High
Burns 12 78.36 Quite High
Injury 14 9.84 Low Low
Cancer 6 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Retinal Neovascularization 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Shh did not affect the expression levels of angiogenic cytokines in cultured cell types. mRNA and protein expression levels of Shh and Ptc were under the detection limit in an uninjured cornea, but Shh but not Ptc was upregulated in a healing, alkali-burned, vascularized cornea.
Transcription (expression) of Ptc in cornea associated with cytokine
1) Confidence 0.49 Published 2009 Journal Molecular Vision Section Abstract Doc Link PMC2684749 Disease Relevance 0.25 Pain Relevance 0.09
On the other hand, Ptc mRNA expression level was unchanged during wound healing in an alkali-burned cornea (data not shown).


Transcription (expression) of Ptc in cornea associated with wound healing
2) Confidence 0.49 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.30 Pain Relevance 0

General Comments

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