INT270451

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Context Info
Confidence 0.26
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.63
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (Gli3) intracellular (Gli3) cilium (Gli3)
DNA binding (Gli3) cytoplasm (Gli3) cytosol (Gli3)
Anatomy Link Frequency
eye 1
cornea 1
Gli3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 86.08 High High
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 21 96.36 Very High Very High Very High
Bacterial Infection 3 76.32 Quite High
Corneal Neovascularization 18 74.76 Quite High
Burns 18 66.12 Quite High
Wound Healing 6 19.44 Low Low
Cancer 9 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 6 5.00 Very Low Very Low Very Low
Hypoxia 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Retinal Neovascularization 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The eye was then enucleated and subjected to HE histology and cryosection for immunohistochemistry of CD31 and nuclear translocation of Gli3, the signaling molecule of Shh.
Localization (translocation) of Gli3 in eye
1) Confidence 0.26 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.17 Pain Relevance 0.04
In these specimens, we then examined the expression of Shh and the nuclear translocation of Gli3.
Localization (translocation) of Gli3
2) Confidence 0.26 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.25 Pain Relevance 0
Topical cyclopmine blocked Gli signaling (blocked translocation of Gli3) and the length of neovascularization in the peripheral cornea post-cauterization as compared with the control vehicle-treated cornea.


Localization (translocation) of Gli3 in cornea
3) Confidence 0.26 Published 2009 Journal Molecular Vision Section Abstract Doc Link PMC2684749 Disease Relevance 0.21 Pain Relevance 0.07

General Comments

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