INT270457

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.30
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cilium (Gli1) DNA binding (Gli1) cytoplasm (Gli1)
cytosol (Gli1) signal transduction (Ptch1) extracellular region (Ptch1)
Ptch1 (Mus musculus)
Gli1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 12 76.00 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 6 99.28 Very High Very High Very High
Skin Cancer 2 98.60 Very High Very High Very High
Malignant Neoplastic Disease 4 97.44 Very High Very High Very High
Necrosis 2 84.76 Quite High
Injury 14 72.08 Quite High
Corneal Neovascularization 12 58.76 Quite High
Wound Healing 4 56.08 Quite High
Burns 12 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon Shh binding to the receptor composed of patched 1 (Ptc) and Smoothend (Smo), the Shh signal transmitter, Gli members, are activated and translocated to the cell nuclei for gene expression regulation.
patched 1 Binding (binding) of Gli
1) Confidence 0.02 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.65 Pain Relevance 0.04
Upon Shh binding to the receptor composed of patched 1 (Ptc) and Smoothend (Smo), the Shh signal transmitter, Gli members, are activated and translocated to the cell nuclei for gene expression regulation.
Ptc Binding (binding) of Gli
2) Confidence 0.02 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.65 Pain Relevance 0.04

General Comments

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