INT270469

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Context Info
Confidence 0.29
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Shh, VEGFA) extracellular region (Shh, VEGFA) anatomical structure formation involved in morphogenesis (Shh)
embryo development (Shh) anatomical structure development (Shh) peptidase activity (Shh)
Anatomy Link Frequency
fibroblasts 2
Shh (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 12 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 14 59.68 Quite High
Corneal Neovascularization 12 38.08 Quite Low
Burns 12 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Wound Healing 4 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 4 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Bacterial Infection 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Retinal Neovascularization 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was reported that Shh upregulates VEGF in endothelial progenitor cells isolated from human peripheral blood but did not upregulate VEGF in HUVECs, primary dermal microvascular endothelial cells, or fibroblasts [24,25].
Shh Positive_regulation (upregulates) of VEGF in fibroblasts
1) Confidence 0.29 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.06 Pain Relevance 0
It was reported that Shh upregulates VEGF in endothelial progenitor cells isolated from human peripheral blood but did not upregulate VEGF in HUVECs, primary dermal microvascular endothelial cells, or fibroblasts [24,25].
Shh Neg (not) Positive_regulation (upregulate) of VEGF in fibroblasts
2) Confidence 0.29 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2684749 Disease Relevance 0.06 Pain Relevance 0

General Comments

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