INT270639

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.21
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Lck) plasma membrane (Lck) kinase activity (Lck)
cytoplasm (Lck)
Lck (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 32 55.60 Quite High
Inflammatory response 15 51.52 Quite High
cytokine 38 48.44 Quite Low
tolerance 14 20.56 Low Low
chemokine 9 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
diabetic neuropathy 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 154 99.48 Very High Very High Very High
Autoimmune Disease 15 87.64 High High
Genetic Predisposition To Disease 4 86.56 High High
Renal Disease 5 79.24 Quite High
INFLAMMATION 48 55.60 Quite High
Pressure And Volume Under Development 4 50.16 Quite High
Cancer 1 44.64 Quite Low
Necrosis 1 44.16 Quite Low
Disease 12 34.32 Quite Low
Infection 4 28.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
But of other SNPs studied, 11 were found only within the diabetic population and some were associated with low LCK protein levels.
LCK Binding (associated) of associated with diabetes mellitus
1) Confidence 0.30 Published 2008 Journal Current Genomics Section Body Doc Link PMC2685644 Disease Relevance 1.06 Pain Relevance 0
Upon ligand binding, the TCR is recruited to the lipid raft where it associates with kinase signaling components such as Lck and Lat.
Lck Binding (associates) of
2) Confidence 0.02 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2781632 Disease Relevance 0.16 Pain Relevance 0.05

General Comments

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