INT270657

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Casp8, Ins1) mitochondrion (Casp8) carbohydrate metabolic process (Ins1)
protein complex (Casp8) cytosol (Casp8) peptidase activity (Casp8)
Casp8 (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 7 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
diabetic neuropathy 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 154 100.00 Very High Very High Very High
Apoptosis 4 100.00 Very High Very High Very High
Leukemia 1 87.12 High High
Multiple Sclerosis 1 69.64 Quite High
Viral Meningitis 1 69.44 Quite High
Autoimmune Disease 15 45.80 Quite Low
Disease 8 10.08 Low Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Diabetes Mellitus-type I 7 5.00 Very Low Very Low Very Low
Renal Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Casp8 (caspase 8) is essential for ß cell apoptosis in type 1 and type 2 diabetes models and in regulating ß cell mass and insulin secretion under physiological conditions [17].
Casp8 Regulation (regulating) of Localization (secretion) of insulin associated with diabetes mellitus and apoptosis
1) Confidence 0.03 Published 2008 Journal Current Genomics Section Body Doc Link PMC2685644 Disease Relevance 0.68 Pain Relevance 0

General Comments

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