INT270680

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.39
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fos) DNA binding (Fos) transcription factor binding (Fos)
Anatomy Link Frequency
neurons 2
ACC 2
Fos (Mus musculus)
Tg(CAG-EGFP)D4Nagy (Mus musculus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 128 99.36 Very High Very High Very High
Pyramidal cell 22 99.20 Very High Very High Very High
Glutamate 22 92.80 High High
imagery 12 88.32 High High
Pain 4 60.36 Quite High
positron emission tomography 6 41.80 Quite Low
nMDA receptor 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Limbic system 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 16 99.62 Very High Very High Very High
Impotence 2 74.52 Quite High
Anxiety Disorder 2 60.72 Quite High
Pain 4 60.36 Quite High
Aggression 2 33.92 Quite Low
Hypoactive Sexual Desire Disorder 2 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using transgenic mice in which the expression of green fluorescent protein (GFP) is controlled by the promoter of the activity-dependent gene c-fos, we found that ACC pyramidal neurons are activated by sexual attraction.
fos Regulation (controlled) of Gene_expression (expression) of GFP in ACC associated with targeted disruption, pyramidal cell and anterior cingulate cortex
1) Confidence 0.03 Published 2009 Journal Mol Brain Section Abstract Doc Link PMC2685783 Disease Relevance 0.10 Pain Relevance 0.52
In the present study, we performed whole-cell patch- clamp recording from neurons in brain slices of transgenic mice in which the expression of green fluorescent protein (GFP) is controlled by the promoter of the activity-dependent gene c-fos.
fos Regulation (controlled) of Gene_expression (expression) of GFP in neurons associated with targeted disruption
2) Confidence 0.03 Published 2009 Journal Mol Brain Section Body Doc Link PMC2685783 Disease Relevance 0.30 Pain Relevance 0.53

General Comments

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