INT270697

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Context Info
Confidence 0.58
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.78
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (MSRA) mitochondrion (MSRA) oxidoreductase activity (MSRA)
aging (MSRA) nucleus (MSRA) cytoplasm (MSRA)
Anatomy Link Frequency
lens cells 2
MSRA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 13 60.88 Quite High
cytokine 8 57.76 Quite High
chemokine 1 51.08 Quite High
cINOD 12 38.08 Quite Low
aspirin 8 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 5 83.12 Quite High
Aging 7 82.12 Quite High
Cancer 64 80.00 Quite High
Stress 58 76.08 Quite High
Diabetes Mellitus 4 66.96 Quite High
Insulin Resistance 3 66.16 Quite High
Colon Cancer 21 63.36 Quite High
Apoptosis 32 62.72 Quite High
INFLAMMATION 16 60.88 Quite High
Squamous Cell Neoplasms 2 58.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mammals have a single MsrA gene that produces the cytosolic, mitochondrial, and nuclear forms of the enzyme [77].
Gene_expression (produces) of MsrA
1) Confidence 0.58 Published 2010 Journal Biol Trace Elem Res Section Body Doc Link PMC2855032 Disease Relevance 0.31 Pain Relevance 0.14
Support for the scavenger role of MsrA has come from recent studies with both PC-12 neuronal cells, in which MsrA was overexpressed [25], and human lens cells, in which MsrA expression was down regulated [26].
Gene_expression (expression) of MsrA in lens cells
2) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2686156 Disease Relevance 0.74 Pain Relevance 0
Support for the scavenger role of MsrA has come from recent studies with both PC-12 neuronal cells, in which MsrA was overexpressed [25], and human lens cells, in which MsrA expression was down regulated [26].
Gene_expression (overexpressed) of MsrA in lens cells
3) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2686156 Disease Relevance 0.73 Pain Relevance 0

General Comments

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