INT270747

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.91
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ETV3) molecular_function (ETV3) biological_process (ETV3)
Anatomy Link Frequency
body 1
ETV3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 43 80.24 Quite High
cytokine 10 27.68 Quite Low
imagery 1 25.96 Quite Low
Inflammatory marker 5 5.00 Very Low Very Low Very Low
depression 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metabolic Syndrome 11 100.00 Very High Very High Very High
Pressure And Volume Under Development 30 99.56 Very High Very High Very High
Obesity 216 99.26 Very High Very High Very High
Weight Loss 64 98.16 Very High Very High Very High
Body Weight 37 94.88 High High
Pulmonary Disease 47 94.24 High High
Abdominal Obesity 2 90.40 High High
INFLAMMATION 52 80.24 Quite High
Dyslipidemia /

Combined Dyslipidemia

2 74.40 Quite High
Insulin Resistance 21 66.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a study in 53 obese women, combining sibutramine (10 to 15 mg/day for one year) with behavior therapy or portion-controlled diet induced greater reductions in body weight than sibutramine alone.41 In a larger study in 224 obese patients, sibutramine (10 to 15 mg/day for one year) with behavior therapy resulted in greater weight loss than either sibutramine or behavior therapy alone.42 The prevalence of metabolic syndrome (MetS) was also reduced more in the former group and this was attributed to the greater weight loss in this group.43
Negative_regulation (reduced) of MetS in body associated with weight loss, body weight, obesity and metabolic syndrome
1) Confidence 0.10 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2686261 Disease Relevance 1.07 Pain Relevance 0
In contrast, obesity was strongly associated with higher prevalence of all components of the MetS including hypertension [32].
Negative_regulation (prevalence) of MetS associated with pressure and volume under development, obesity and metabolic syndrome
2) Confidence 0.10 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC3010654 Disease Relevance 1.77 Pain Relevance 0.04

General Comments

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