INT270824

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Context Info
Confidence 0.34
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7, Panx1) protein complex (P2rx7, Panx1) plasma membrane (P2rx7, Panx1)
cell morphogenesis (P2rx7) endoplasmic reticulum (Panx1) mitochondrion organization (P2rx7)
P2rx7 (Mus musculus)
Panx1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 18 94.08 High High
Inflammation 20 93.72 High High
Inflammatory stimuli 4 12.72 Low Low
antagonist 6 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 93.72 High High
Apoptosis 2 61.28 Quite High
Disease 2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pannexin-1 is a recently identified protein found to physically associate with the P2X7R.
P2X7R Binding (associate) of Pannexin-1
1) Confidence 0.34 Published 2009 Journal Purinergic Signal Section Abstract Doc Link PMC2686830 Disease Relevance 0.09 Pain Relevance 0.09
Under resting conditions, P2X7R may keep panx1 under negative regulation via direct interaction.
P2X7R Binding (interaction) of panx1
2) Confidence 0.30 Published 2009 Journal Purinergic Signal Section Body Doc Link PMC2686830 Disease Relevance 0.06 Pain Relevance 0

General Comments

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