INT270825

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) mitochondrion organization (P2rx7)
protein complex (P2rx7) transmembrane transport (P2rx7) cytoplasm (P2rx7)
P2rx7 (Mus musculus)
Slc37a4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 9 75.32 Quite High
Inflammatory stimuli 2 33.40 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 33.04 Quite Low
Disease 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A third hypothesis regarding panx1-mediated activation of the inflammasome is that extracellular ATP activates the P2X7R, which in turn activates panx1 hemichannel (or transporter) activity to directly transport ATP into the cell.
P2X7R Positive_regulation (activates) of transporter
1) Confidence 0.01 Published 2009 Journal Purinergic Signal Section Body Doc Link PMC2686830 Disease Relevance 0 Pain Relevance 0.04

General Comments

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