INT270833

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Panx1) endoplasmic reticulum (Panx1) intracellular (CASP1)
protein complex (Panx1) cell-cell signaling (Panx1) cytoplasm (CASP1)
CASP1 (Homo sapiens)
Panx1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 9 87.12 High High
Inflammation 10 86.76 High High
addiction 2 18.48 Low Low
Potency 1 8.40 Low Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 86.76 High High
Toxicity 1 50.16 Quite High
Disease 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 10panx1 peptide did not inhibit caspase-1 activity per se in cell-free assays, so ruling out a direct chemical or enzymatic interaction with caspase-1.
caspase-1 Binding (interaction) of 10panx1
1) Confidence 0.02 Published 2009 Journal Purinergic Signal Section Body Doc Link PMC2686830 Disease Relevance 0.14 Pain Relevance 0.09

General Comments

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