INT270834

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CBX1) transport (Panx1) endoplasmic reticulum (Panx1)
plasma membrane (Panx1) nucleus (CBX1) enzyme binding (CBX1)
CBX1 (Homo sapiens)
Panx1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 2 70.12 Quite High
cytokine 9 63.08 Quite High
Inflammation 10 62.72 Quite High
antagonist 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 69.80 Quite High
Disease 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CBX, siRNA gene silencing of panx1 protein, and 10panx1 inhibitory peptide all inhibit P2X7R-mediated IL-1?
CBX Negative_regulation (inhibit) of Transcription (peptide) of 10panx1
1) Confidence 0.06 Published 2009 Journal Purinergic Signal Section Body Doc Link PMC2686830 Disease Relevance 0.13 Pain Relevance 0.10

General Comments

This test has worked.

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