INT270835

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (P2rx7, DPEP1) transport (P2rx7) cell morphogenesis (P2rx7)
mitochondrion organization (P2rx7) protein complex (P2rx7) transmembrane transport (P2rx7)
P2rx7 (Mus musculus)
DPEP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 2 85.24 High High
cytokine 9 52.96 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 84.88 Quite High
Disease 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This novel hypothesis is based on observations that cytosolic delivery of the bacterial PAMP lysosomic muramyl dipeptide (MDP) activated the inflammasome in a manner similar to P2X7R and that P2X7R activation induced a panx1-dependent lysosome-to-cytosol translocation of MDP [61, 62].
Positive_regulation (activation) of P2X7R Positive_regulation (induced) of Localization (translocation) of MDP
1) Confidence 0.04 Published 2009 Journal Purinergic Signal Section Body Doc Link PMC2686830 Disease Relevance 0.08 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox