INT270836

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CBX1) transport (Panx1) endoplasmic reticulum (Panx1)
plasma membrane (Panx1) nucleus (CBX1) enzyme binding (CBX1)
Anatomy Link Frequency
macrophage 1
CBX1 (Homo sapiens)
Panx1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory stimuli 2 45.68 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 9 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 45.68 Quite Low
Apoptosis 1 13.40 Low Low
Disease 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This idea that panx1 is unlikely to be directly involved with ion flux in macrophage is further supported by a recent study where inhibition of panx1 by CBX prevented ATP-mediated IL-1?
CBX Negative_regulation (inhibition) of panx1 in macrophage
1) Confidence 0.09 Published 2009 Journal Purinergic Signal Section Body Doc Link PMC2686830 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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