INT270935

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Context Info
Confidence 0.31
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) aging (Slc6a3)
Golgi apparatus (Cpe) plasma membrane (Slc6a3) transmembrane transport (Slc6a3)
Cpe (Rattus norvegicus)
Slc6a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 93 96.72 Very High Very High Very High
Kinase C 45 89.68 High High
gABA 6 45.84 Quite Low
Neuropeptide 6 8.00 Low Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
cocaine 3 5.00 Very Low Very Low Very Low
Ventral tegmentum 3 5.00 Very Low Very Low Very Low
monoamine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 9 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low
Obesity 6 5.00 Very Low Very Low Very Low
Drug Dependence 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Neurological Disease 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To explore this possibility, we first tested whether CPE had any effect on the phosphrylation levels of DAT.
CPE Spec (whether) Regulation (effect) of Phosphorylation (phosphrylation) of DAT
1) Confidence 0.31 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.16
The exact mechanism for CPE's effects on DAT phosphorylation and its relationship with cell surface DAT expression require further investigation.
CPE Regulation (effects) of Phosphorylation (phosphorylation) of DAT
2) Confidence 0.31 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.28
We concluded that CPE-mediated modulation of DAT trafficking, membrane expression and phosphorylation was facilitated by the CPE-DAT physical coupling.
CPE Regulation (modulation) of Phosphorylation (phosphorylation) of DAT
3) Confidence 0.12 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.13

General Comments

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