INT270943

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Cpe) intracellular (Prkcg) response to stress (Prkcg)
cytoplasm (Prkcg) cytosol (Prkcg) extracellular space (Cpe)
Prkcg (Rattus norvegicus)
Cpe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 30 100.00 Very High Very High Very High
Dopamine 62 74.08 Quite High
gABA 4 70.96 Quite High
monoamine 2 24.40 Low Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
Ventral tegmentum 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is possible that the interaction with CPE may mask the PKC phosphorylation site on DAT.
PKC Binding (interaction) of CPE associated with kinase c
1) Confidence 0.05 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.32
As shown in Fig 4B, PMA treatment reduced the association between CPE and DAT as compared with non-treated COS-7 cells, implying that CPE preferentially interacted with non-PKC phosphorylated forms of DAT.


non-PKC Binding (interacted) of CPE associated with kinase c
2) Confidence 0.04 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.26

General Comments

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