INT270948

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) aging (Slc6a3)
Golgi apparatus (Cpe) plasma membrane (Slc6a3) transmembrane transport (Slc6a3)
Cpe (Rattus norvegicus)
Slc6a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 31 96.24 Very High Very High Very High
addiction 2 94.64 High High
Kinase C 15 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Ventral tegmentum 1 5.00 Very Low Very Low Very Low
monoamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 3 95.52 Very High Very High Very High
Drug Dependence 2 94.84 High High
Obesity 2 94.08 High High
Stress 3 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, our results reveal a novel role for CPE in the regulation of DAT trafficking and DAT-mediated DA uptake, which may provide a novel target in the treatment of dopamine-governed diseases such as drug addiction and obesity.



CPE Regulation (role) of Regulation (regulation) of DAT associated with drug dependence, addiction, dopamine, obesity and disease
1) Confidence 0.14 Published 2009 Journal Mol Brain Section Abstract Doc Link PMC2687442 Disease Relevance 0.28 Pain Relevance 0.23

General Comments

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