INT270954

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) aging (Slc6a3)
Golgi apparatus (Cpe) plasma membrane (Slc6a3) transmembrane transport (Slc6a3)
Anatomy Link Frequency
plasma 3
Cpe (Rattus norvegicus)
Slc6a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 62 85.12 High High
Neuropeptide 4 40.16 Quite Low
Kinase C 30 10.32 Low Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
Ventral tegmentum 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coexpression of CPE with DAT changed the diffuse DAT expression throughout the cell to stronger plasma membrane localization and suggests the interaction occur intracellularlly.
Gene_expression (Coexpression) of CPE in plasma Positive_regulation (changed) of Gene_expression (expression) of DAT in plasma
1) Confidence 0.23 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.10
As shown in Fig 3, coexpression of CPE increased the levels of both total DAT and cell surface DAT to about ~20% (Fig. 3A, B).
Gene_expression (coexpression) of CPE Positive_regulation (increased) of Gene_expression (levels) of DAT
2) Confidence 0.20 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.18

General Comments

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