INT270969

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) Golgi apparatus (Cpe)
Anatomy Link Frequency
plasma 2
Cpe (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 93 98.40 Very High Very High Very High
Neuropeptide 6 38.00 Quite Low
Kinase C 45 10.32 Low Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
cocaine 3 5.00 Very Low Very Low Very Low
Ventral tegmentum 3 5.00 Very Low Very Low Very Low
monoamine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 9 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low
Obesity 6 5.00 Very Low Very Low Very Low
Drug Dependence 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Neurological Disease 3 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Schizophrenia 3 5.00 Very Low Very Low Very Low
Cognitive Disorder 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these data indicated that the binding of DAT-CT tail583–620 sequences to CPE was both sufficient and necessary for the expression of CPE- mediated functional regulation of the DA translocation process.


Regulation (sufficient) of Gene_expression (expression) of CPE associated with dopamine
1) Confidence 0.27 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.25
Coexpression of CPE with DAT changed the diffuse DAT expression throughout the cell to stronger plasma membrane localization and suggests the interaction occur intracellularlly.
Regulation (changed) of Gene_expression (Coexpression) of CPE in plasma
2) Confidence 0.24 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.10
Therefore, we next examined if DAT cell surface expression levels change upon coexpression of CPE by using a cell-based ELISA assay to quantify changes at the cell surface and total DAT levels [27-29].
Spec (examined) Regulation (change) of Gene_expression (coexpression) of CPE
3) Confidence 0.16 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.19

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox