INT270974

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Slc6a3) plasma membrane (Slc6a3) transmembrane transport (Slc6a3)
Slc6a3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 62 88.16 High High
Kinase C 30 19.44 Low Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
Ventral tegmentum 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Obesity 4 5.00 Very Low Very Low Very Low
Drug Dependence 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Schizophrenia 2 5.00 Very Low Very Low Very Low
Cognitive Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggested that CPE modulated DAT via a posttranslational mechanism, which possibly included reduced degradation of surface DAT.
Negative_regulation (reduced) of Protein_catabolism (degradation) of DAT
1) Confidence 0.42 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0
Functional changes caused by CPE could be attributed to enhanced DAT expression and subsequent increase in DAT cell surface localization, due to decreased DAT degradation.
Negative_regulation (decreased) of Protein_catabolism (degradation) of DAT
2) Confidence 0.31 Published 2009 Journal Mol Brain Section Abstract Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox