INT270983

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.12
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpe) extracellular space (Cpe) Golgi apparatus (Cpe)
peroxisome (GSTK1) intracellular (GSTK1)
Cpe (Rattus norvegicus)
GSTK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Substantia nigra 4 73.60 Quite High
Dopamine 124 50.00 Quite Low
anesthesia 4 44.80 Quite Low
Kinase C 60 5.00 Very Low Very Low Very Low
Neurotransmitter 8 5.00 Very Low Very Low Very Low
Neuropeptide 8 5.00 Very Low Very Low Very Low
addiction 8 5.00 Very Low Very Low Very Low
gABA 8 5.00 Very Low Very Low Very Low
cocaine 4 5.00 Very Low Very Low Very Low
Ventral tegmentum 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 12 61.52 Quite High
Disease 12 5.00 Very Low Very Low Very Low
Obesity 8 5.00 Very Low Very Low Very Low
Drug Dependence 8 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Neurological Disease 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Schizophrenia 4 5.00 Very Low Very Low Very Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown in Figure 1C, in vitro translated [35S]-CPE probe hybridized with GST-DAT-CT but not GST-DAT-NT or GST alone, indicating the specificity of the direct protein-protein interaction between CPE and DAT-CT.
CPE Binding (hybridized) of GST
1) Confidence 0.01 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0
As shown in Figure 1C, in vitro translated [35S]-CPE probe hybridized with GST-DAT-CT but not GST-DAT-NT or GST alone, indicating the specificity of the direct protein-protein interaction between CPE and DAT-CT.
CPE Binding (hybridized) of GST
2) Confidence 0.01 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0
The results shown in Fig. 1B demonstrated that GST-DAT-CT could selectively precipitate CPE from solubilized rat striatal tissue whereas GST alone was unable to purify CPE.
CPE Binding (precipitate) of GST
3) Confidence 0.01 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0.06 Pain Relevance 0.04
Moreover, to exclude the possibility of CPE non-specifically binding to GST fusion peptides, intracellular N-terminal domain of DAT was also employed as a control.
CPE Binding (binding) of GST
4) Confidence 0.01 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

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