INT270999

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Context Info
Confidence 0.44
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.81
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CYSLTR2) cellular_component (CYSLTR2) signal transducer activity (CYSLTR2)
CYSLTR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 62 88.84 High High
antagonist 10 88.44 High High
adenocard 2 74.72 Quite High
Inflammation 10 14.08 Low Low
cINOD 6 5.00 Very Low Very Low Very Low
COX2 4 5.00 Very Low Very Low Very Low
Antihistamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 138 99.92 Very High Very High Very High
Pressure And Volume Under Development 84 99.60 Very High Very High Very High
Genetic Predisposition To Disease 4 94.36 High High
Hypersensitivity 8 89.56 High High
Urticaria 40 87.28 High High
Rhinitis 6 80.88 Quite High
Nasal Polyps 4 20.80 Low Low
Chronic Sinusitis 2 20.00 Low Low
INFLAMMATION 10 14.08 Low Low
Hypersensitivity Pneumonitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased expression of CYSLTR1 with CYLSTR1 and CYSLTR2 polymorphisms are new findings in AIA, while the ALOX5 promoter polymorphism has been noted in AIU.
Positive_regulation (Increased) of Gene_expression (expression) of CYSLTR2 associated with asthma and pressure and volume under development
1) Confidence 0.44 Published 2006 Journal Yonsei Medical Journal Section Abstract Doc Link PMC2687575 Disease Relevance 1.82 Pain Relevance 0.17
It has been suggested that the activity of the leukotriene C4 synthase gene (LTC4S), a key enzyme in Cys-LT synthesis, is genetically regulated in the pathogenesis of AIA.
Positive_regulation (enzyme) of Gene_expression (synthesis) of Cys-LT associated with asthma
2) Confidence 0.38 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687575 Disease Relevance 0.99 Pain Relevance 0.11

General Comments

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