INT271087

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pcna) intracellular (Pcna) DNA binding (Pcna)
transcription factor binding (Pcna) cytoplasm (Pcna)
Anatomy Link Frequency
BxPC-3 1
Pcna (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 3 5.00 Very Low Very Low Very Low
colic 1 5.00 Very Low Very Low Very Low
neuralgia 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 15 97.06 Very High Very High Very High
Death 16 88.96 High High
Disease 4 88.84 High High
Apoptosis 32 68.48 Quite High
Cancer 22 28.00 Quite Low
Adenocarcinoma 1 25.72 Quite Low
Intestinal Cancer 1 24.36 Low Low
Malignant Neoplastic Disease 3 19.80 Low Low
Sprains And Strains 1 16.16 Low Low
Ulcers 1 15.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore we examined the anticancer activities of [6]-gingerol, and investigated its mechanism in two different pancreatic cancer cell lines, HPAC with wt p53 or BxPC-3 with mutant p53. [6]-Gingerol's antiproliferative effects are associated with changes in the expression or phosphorylation of Cyclin A, Cdks, p21 and Rb, and most commonly, causes cell cycle arrest at the G1 phase.
Phosphorylation (phosphorylation) of Cyclin in BxPC-3 associated with pancreatic cancer
1) Confidence 0.01 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687755 Disease Relevance 0.65 Pain Relevance 0

General Comments

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