INT271160

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (SYNE1) cell death (SYNE1) Golgi apparatus (SYNE1)
nucleolus (SYNE1) cytoskeleton (SYNE1) nucleus (SYNE1)
SYNE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
noradrenaline 114 99.32 Very High Very High Very High
Locus ceruleus 696 97.44 Very High Very High Very High
Duloxetine 4 95.12 Very High Very High Very High
cocaine 12 90.60 High High
antidepressant 6 79.36 Quite High
cerebral cortex 20 69.92 Quite High
adenocard 10 59.60 Quite High
antagonist 52 58.08 Quite High
Desipramine 2 57.16 Quite High
tricyclic antidepressant 2 56.68 Quite High
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 16 98.04 Very High Very High Very High
Pressure Volume 2 Under Development 2 88.36 High High
Miosis 16 82.36 Quite High
Increased Venous Pressure Under Development 2 77.24 Quite High
Salivary Gland Disease 8 72.80 Quite High
Sleep Disorders 30 65.80 Quite High
Mydriatic 26 48.16 Quite Low
Urological Neuroanatomy 18 16.28 Low Low
Obesity 2 5.72 Low Low
Anxiety Disorder 132 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Potentiation of the noradrenergic inhibition of the salivatory nuclei, as a result of noradrenaline reuptake inhibition, is expected to result in a reduction in salivary output.
Negative_regulation (inhibition) of salivatory nuclei associated with noradrenaline
1) Confidence 0.00 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687931 Disease Relevance 0.43 Pain Relevance 0.34
Reserpine-induced noradrenaline depletion has also been demonstrated to be associated with an increase in salivary output [43], which is likely to be due to the removal of the tonic noradrenergic inhibition of salivatory nuclei.


Negative_regulation (inhibition) of salivatory nuclei associated with noradrenaline
2) Confidence 0.00 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2687931 Disease Relevance 0.24 Pain Relevance 0.47

General Comments

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