INT271282

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Stat1, Usp18) peptidase activity (Usp18) nucleolus (Stat1)
enzyme binding (Stat1) DNA binding (Stat1) cytoplasm (Stat1)
Stat1 (Mus musculus)
Usp18 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 40 87.16 High High
Cancer 190 84.72 Quite High
Metastasis 38 64.24 Quite High
Dna Damage 20 39.44 Quite Low
Renal Cancer 2 28.44 Quite Low
Skin Cancer 10 6.96 Low Low
Breast Cancer 12 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, STAT1 has been reported to control pro-survival genes such as MCL1 [58], IFITM1 or Leu-13 [59], multidrug resistance vault proteins [60], and USP18 (UBP43), which mediate protection from IFN-induced cytotoxicity [61].
STAT1 Regulation (control) of USP18
1) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2688034 Disease Relevance 0.68 Pain Relevance 0
Indeed, STAT1 has been reported to control pro-survival genes such as MCL1 [58], IFITM1 or Leu-13 [59], multidrug resistance vault proteins [60], and USP18 (UBP43), which mediate protection from IFN-induced cytotoxicity [61].
STAT1 Regulation (control) of UBP43
2) Confidence 0.30 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2688034 Disease Relevance 0.68 Pain Relevance 0

General Comments

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