INT271350

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.66
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (MPO, TIMP1) mitochondrion (MPO) extracellular space (MPO)
extracellular region (TIMP1) oxidoreductase activity (MPO) nucleus (MPO)
Anatomy Link Frequency
plaque 1
MPO (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 5 100.00 Very High Very High Very High
Bioavailability 1 96.88 Very High Very High Very High
Inflammation 19 88.72 High High
ischemia 24 62.20 Quite High
Angina 34 41.56 Quite Low
cytokine 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 28 100.00 Very High Very High Very High
Rupture 8 98.68 Very High Very High Very High
Atherosclerotic Plaque 10 98.08 Very High Very High Very High
Stress 7 89.60 High High
INFLAMMATION 21 88.72 High High
Coronary Artery Disease 26 73.04 Quite High
Acute Coronary Syndrome 70 71.84 Quite High
Thrombosis 3 62.80 Quite High
Cv Unclassified Under Development 14 62.20 Quite High
Necrosis 23 47.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, MPO has been showed to activate metalloproteinases and promote destabilization and rupture of the atherosclerotic plaque surface.
MPO Positive_regulation (activate) of metalloproteinases in plaque associated with atherosclerotic plaque, rupture, metalloproteinase and urological neuroanatomy
1) Confidence 0.05 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 1.66 Pain Relevance 0.29

General Comments

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