INT271368

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (PAPPA) peptidase activity (PAPPA) extracellular region (PAPPA)
Anatomy Link Frequency
plaques 2
PAPPA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 5 58.64 Quite High
Angina 34 48.08 Quite Low
Inflammation 19 43.80 Quite Low
ischemia 24 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerotic Plaque 10 99.84 Very High Very High Very High
Acute Coronary Syndrome 70 99.16 Very High Very High Very High
Necrosis 23 82.48 Quite High
Death 21 64.60 Quite High
Myocardial Infarction 41 48.40 Quite Low
Angina 34 48.08 Quite Low
INFLAMMATION 21 43.80 Quite Low
Pathologic Processes 1 37.28 Quite Low
Atherosclerosis 5 16.48 Low Low
Down Syndrome 1 8.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is difficult to measure PAPP-A present in atherosclerotic plaques by immunoassays because they are designed to detect PAPP-A present in pregnancy sera.
Negative_regulation (measure) of Localization (present) of PAPP-A in plaques associated with atherosclerotic plaque
1) Confidence 0.41 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688349 Disease Relevance 0.65 Pain Relevance 0.06

General Comments

This test has worked.

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