INT271419

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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SMAD3) nucleoplasm (SMAD3) transport (SMAD3)
plasma membrane (SMAD3) nucleus (SMAD3) intracellular (SMAD3)
SMAD3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Action potential 3 69.76 Quite High
Inflammation 7 5.00 Very Low Very Low Very Low
Nerve growth factor 6 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
qutenza 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
Sciatic nerve 3 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 4 75.00 Quite High
Cough 91 38.00 Quite Low
Asthma 16 5.00 Very Low Very Low Very Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Airway Remodeling 9 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Stress 5 5.00 Very Low Very Low Very Low
Nicotine Addiction 5 5.00 Very Low Very Low Very Low
Fibrosis 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The negatively regulated genes included FAS, TNFR, COL6A1, JAM2, FOXQ1, FOXO1, NESTIN, SMAD3, SLIT3, DKK1, WNT5A, BMP1, and GLIS3 which are implicated in differentiation processes as well as a number of novel genes.
Localization (implicated) of SMAD3
1) Confidence 0.11 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2747014 Disease Relevance 0.13 Pain Relevance 0.03
Immunofluorescence was carried out to detect the nuclear translocation of Smad2/3 in human bronchial biopsy sections.
Localization (translocation) of Smad2/3
2) Confidence 0.03 Published 2009 Journal Respir Res Section Body Doc Link PMC2688489 Disease Relevance 0 Pain Relevance 0

General Comments

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