INT271433

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Context Info
Confidence 0.55
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Eln) extracellular region (Eln) proteinaceous extracellular matrix (Eln)
extracellular matrix organization (Eln)
Anatomy Link Frequency
bladders 1
Eln (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 94 5.00 Very Low Very Low Very Low
cytokine 16 5.00 Very Low Very Low Very Low
Spinal cord 12 5.00 Very Low Very Low Very Low
fibrosis 10 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
halothane 6 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperplasia 6 99.76 Very High Very High Very High
Hypertrophy 8 99.12 Very High Very High Very High
Spinal Cord Injury 124 97.28 Very High Very High Very High
Injury 22 78.84 Quite High
Disease 12 29.04 Quite Low
INFLAMMATION 104 5.00 Very Low Very Low Very Low
Infection 30 5.00 Very Low Very Low Very Low
Overactive Bladder 12 5.00 Very Low Very Low Very Low
Fibrosis 10 5.00 Very Low Very Low Very Low
Diabetes Mellitus 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Up-regulation of tropoelastin and lysyl oxidase was further confirmed and quantified at the mRNA level using total RNA collected from three to four bladders each of normal and post-SCI (3 days, 7 days, and 25 days) rats and TaqMan analysis according to the standard protocols with the Mx3000P qPCR apparatus (Stratagene, La Jolla, CA), as described previously [10]. mRNA expression for tropoelastin and lysyl oxidase was found to be significantly higher at 3 and 7 days post-SCI as compared to normal, and returned to normal levels at 25 days.
Transcription (expression) of tropoelastin in bladders associated with spinal cord injury
1) Confidence 0.55 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2688838 Disease Relevance 0.66 Pain Relevance 0
The expression of tropoelastin and lysyl oxidase mRNA were 8- and 6-fold higher, respectively, in SCI rats at 3 days as compared to normal rats.
Transcription (expression) of tropoelastin associated with spinal cord injury
2) Confidence 0.55 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2688838 Disease Relevance 0.54 Pain Relevance 0

General Comments

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