INT271460

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.57
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (Rg9mtd2)
Anatomy Link Frequency
blood 1
anterior 1
brain 1
Rg9mtd2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 222 99.90 Very High Very High Very High
bradykinin 216 99.66 Very High Very High Very High
b2 receptor 177 78.56 Quite High
imagery 24 5.00 Very Low Very Low Very Low
Thalamus 9 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 225 100.00 Very High Very High Very High
Cancer 300 99.68 Very High Very High Very High
Brain Tumor 132 96.98 Very High Very High Very High
Malignant Neoplastic Disease 12 50.00 Quite Low
Solid Tumor 9 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the case of anterior brain RG-2 gliomas, our findings suggest that observed increases in Gd-DTPA AUC due to the systemic infusion of bradykinin B2 agonists are dependent on RG-2 glioma tumor volume and therefore, the transvascular accumulation of Gd-DTPA increases with increasing tumor volume.
Regulation (dependent) of RG-2 in anterior associated with cancer, agonist, bradykinin and glioma
1) Confidence 0.05 Published 2009 Journal J Transl Med Section Body Doc Link PMC2689161 Disease Relevance 1.26 Pain Relevance 0.40
By modeling the blood and brain tumor tissue Gd concentration curves of the 1st Gd-DTPA bolus, with the 2-compartment 3-parameter generalized kinetic model[48], we calculated the baseline RG-2 glioma tissue vascular parameter values prior to intravenous bradykinin B2 agonist infusion.
Regulation (values) of RG-2 in brain associated with agonist, bradykinin, glioma and brain tumor
2) Confidence 0.03 Published 2009 Journal J Transl Med Section Body Doc Link PMC2689161 Disease Relevance 1.15 Pain Relevance 0.15
By modeling the blood and brain tumor tissue Gd concentration curves of the 1st Gd-DTPA bolus, with the 2-compartment 3-parameter generalized kinetic model[48], we calculated the baseline RG-2 glioma tissue vascular parameter values prior to intravenous bradykinin B2 agonist infusion.
Regulation (values) of RG-2 in blood associated with agonist, bradykinin, glioma and brain tumor
3) Confidence 0.01 Published 2009 Journal J Transl Med Section Body Doc Link PMC2689161 Disease Relevance 1.15 Pain Relevance 0.15

General Comments

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