INT271466

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.11
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
anterior 2
brain 2
Gd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 148 100.00 Very High Very High Very High
bradykinin 144 100.00 Very High Very High Very High
b2 receptor 118 93.12 High High
imagery 16 5.00 Very Low Very Low Very Low
Thalamus 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 150 99.64 Very High Very High Very High
Cancer 200 99.36 Very High Very High Very High
Brain Tumor 88 98.44 Very High Very High Very High
Malignant Neoplastic Disease 8 50.00 Quite Low
Solid Tumor 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the case of anterior brain RG-2 gliomas, our findings suggest that observed increases in Gd-DTPA AUC due to the systemic infusion of bradykinin B2 agonists are dependent on RG-2 glioma tumor volume and therefore, the transvascular accumulation of Gd-DTPA increases with increasing tumor volume.
Regulation (dependent) of Positive_regulation (increases) of Gd-DTPA in anterior associated with cancer, agonist, bradykinin and glioma
1) Confidence 0.09 Published 2009 Journal J Transl Med Section Body Doc Link PMC2689161 Disease Relevance 1.34 Pain Relevance 0.41
To quantify the effect of the increase in blood half-life of Gd-DTPA on the accumulation of Gd-DTPA in the brain tumor tissue extravascular space, we calculated the percent change in the Gd-DTPA AUC between the 1st and 2nd Gd-DTPA concentration curve profiles of RG-2 glioma brain tumor tissue.
Regulation (effect) of Positive_regulation (increase) of Gd-DTPA in brain associated with glioma and brain tumor
2) Confidence 0.05 Published 2009 Journal J Transl Med Section Body Doc Link PMC2689161 Disease Relevance 0.77 Pain Relevance 0.22

General Comments

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