INT271590

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Context Info
Confidence 0.35
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2rx4) transport (P2rx4) plasma membrane (P2rx4)
Anatomy Link Frequency
spinal cord 2
P2rx4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 11 100.00 Very High Very High Very High
intrathecal 14 98.94 Very High Very High Very High
allodynia 2 97.12 Very High Very High Very High
Neuropathic pain 15 93.52 High High
Brush evoked pain 20 86.72 High High
antagonist 1 86.32 High High
withdrawal 7 77.52 Quite High
Dorsal horn 19 69.84 Quite High
Peripheral nerve injury 5 47.68 Quite Low
cytokine 3 31.60 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 37 97.12 Very High Very High Very High
Nervous System Injury 17 46.80 Quite Low
Pain 9 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low
Paralysis 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After intrathecal PDGF-BB (10 pmol) administration, the level of mRNA expression of P2X4 receptor in the spinal cord was significantly increased on day 3 (P < 0.05) (Figure 4A).
Positive_regulation (increased) of Transcription (expression) of P2X4 in spinal cord associated with spinal cord and intrathecal
1) Confidence 0.35 Published 2009 Journal Mol Pain Section Body Doc Link PMC2690582 Disease Relevance 0.40 Pain Relevance 0.70

General Comments

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