INT271601

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Pdgfa, Pdgfrl) extracellular space (Pdgfa) molecular_function (Pdgfrl)
cellular_component (Pdgfrl) biological_process (Pdgfrl)
Anatomy Link Frequency
neurons 1
Pdgfa (Mus musculus)
Pdgfrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Peripheral nerve injury 5 98.54 Very High Very High Very High
intrathecal 14 96.40 Very High Very High Very High
Brush evoked pain 20 90.88 High High
withdrawal 7 86.88 High High
Stimulus evoked pain 2 85.92 High High
Neuropathic pain 15 83.92 Quite High
Dorsal horn neuron 8 82.56 Quite High
Thermal hyperalgesia 1 78.44 Quite High
allodynia 2 49.84 Quite Low
Dorsal horn 19 33.08 Quite Low
Disease Link Frequency Relevance Heat
Nervous System Injury 17 98.54 Very High Very High Very High
Neuropathic Pain 37 90.88 High High
Hypersensitivity 2 85.92 High High
Pain 9 85.24 High High
Hyperalgesia 1 78.44 Quite High
Paralysis 2 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used the PDGF-BB isoform in all experiments in this study because PDGF-B chain expression is induced after peripheral nerve injury [25], neurons throughout the CNS contain the PDGF-B chain [26], and the PDGF-B chain activates both PDGFR?
PDGF Positive_regulation (activates) of PDGFR in neurons associated with nervous system injury and peripheral nerve injury
1) Confidence 0.03 Published 2009 Journal Mol Pain Section Body Doc Link PMC2690582 Disease Relevance 0.83 Pain Relevance 0.91

General Comments

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