INT271602

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.86
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Pdgfa, Pdgfrl) extracellular space (Pdgfa) molecular_function (Pdgfrl)
cellular_component (Pdgfrl) biological_process (Pdgfrl)
Anatomy Link Frequency
dorsal horn 1
Pdgfa (Mus musculus)
Pdgfrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 38 98.52 Very High Very High Very High
Brush evoked pain 40 89.60 High High
withdrawal 14 83.00 Quite High
Neuropathic pain 30 81.88 Quite High
Pain 14 77.28 Quite High
intrathecal 28 77.08 Quite High
hyperexcitability 2 71.24 Quite High
Dorsal horn neuron 16 60.16 Quite High
cytokine 6 58.80 Quite High
Spinal cord 22 54.24 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 74 89.60 High High
Pain 18 77.28 Quite High
Nervous System Injury 34 69.44 Quite High
Hyperalgesia 2 45.84 Quite Low
Hypersensitivity 4 30.56 Quite Low
Paralysis 4 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PDGF-AA, -BB, -AB, and -CC bind to PDGFR?
PDGF Binding (bind) of PDGFR
1) Confidence 0.02 Published 2009 Journal Mol Pain Section Body Doc Link PMC2690582 Disease Relevance 0.51 Pain Relevance 0.68
phosphorylation in the dorsal horn (Figure 3F), indicating that minocycline does not directly interrupt the PDGF binding to the PDGFR?
PDGF Binding (binding) of PDGFR in dorsal horn associated with dorsal horn
2) Confidence 0.02 Published 2009 Journal Mol Pain Section Body Doc Link PMC2690582 Disease Relevance 0.35 Pain Relevance 0.57

General Comments

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