INT271605

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (AKT2) transport (AKT2) mitochondrion (AKT2)
carbohydrate metabolic process (AKT2) cytoplasm (AKT2) cytosol (AKT2)
Anatomy Link Frequency
neurons 2
AKT2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Brush evoked pain 20 99.00 Very High Very High Very High
intrathecal 14 97.24 Very High Very High Very High
Peripheral nerve injury 5 96.68 Very High Very High Very High
Stimulus evoked pain 2 94.04 High High
Neuropathic pain 15 92.04 High High
Dorsal horn neuron 8 90.68 High High
Thermal hyperalgesia 1 86.56 High High
withdrawal 7 69.92 Quite High
Dorsal horn 19 41.20 Quite Low
Pain 7 34.36 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 37 99.00 Very High Very High Very High
Nervous System Injury 17 96.24 Very High Very High Very High
Hypersensitivity 2 94.04 High High
Pain 9 93.36 High High
Hyperalgesia 1 86.56 High High
Paralysis 2 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We used the PDGF-BB isoform in all experiments in this study because PDGF-B chain expression is induced after peripheral nerve injury [25], neurons throughout the CNS contain the PDGF-B chain [26], and the PDGF-B chain activates both PDGFR?
Regulation (used) of Gene_expression (isoform) of -BB in neurons associated with nervous system injury and peripheral nerve injury
1) Confidence 0.44 Published 2009 Journal Mol Pain Section Body Doc Link PMC2690582 Disease Relevance 0.81 Pain Relevance 0.87

General Comments

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