INT271762

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.66
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (HAND1) nucleolus (HAND1) nucleus (HAND1)
enzyme binding (HAND1) transcription factor binding (HAND1) cytoplasm (HAND1)
Anatomy Link Frequency
brain 1
autonomic nervous system 1
HAND1 (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 55 100.00 Very High Very High Very High
Central nervous system 19 9.92 Low Low
alcohol 5 5.00 Very Low Very Low Very Low
Neurobehavioral 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 176 100.00 Very High Very High Very High
Depression 63 100.00 Very High Very High Very High
Disease 38 100.00 Very High Very High Very High
Dementia 27 99.50 Very High Very High Very High
Coronary Artery Disease 79 97.56 Very High Very High Very High
Diabetes Mellitus 3 71.20 Quite High
Myocardial Infarction 4 69.52 Quite High
Infection 17 69.40 Quite High
Anxiety Disorder 1 50.92 Quite High
Stress 2 50.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The clinical spectrum of the disease has shifted from the severe and devastating form of dementia commonly encountered in association with advanced AIDS (typically end-stage disease) before the introduction of protease inhibitors and highly active antiretroviral therapy, to the milder and more manageable forms of HAND.
HAND Binding (association) of associated with dementia, acquired immune deficiency syndrome or hiv infection and disease
1) Confidence 0.10 Published 2009 Journal Neuropsychol Rev Section Body Doc Link PMC2690834 Disease Relevance 1.09 Pain Relevance 0
Second, we investigated the association of ANS activity (HR, HRV, and plasma NE levels) impact of depression and autonomic nervous system activity on CABG outcomes.
autonomic nervous system Binding (association) of in autonomic nervous system associated with depression
2) Confidence 0.04 Published 2010 Journal J Cardiothorac Surg Section Body Doc Link PMC2882369 Disease Relevance 1.96 Pain Relevance 0.31
The HBSD is unique compared to other sequence databases, such as the LANL HIV Sequence Database or Genbank, because of its specific focus on HIV in the brain, its stringent inclusion of only clonal sequences from patients with brain sequences, and its rigorous curation with detailed clinical, patient, and HAND annotations.
HAND Binding (curation) of in brain associated with acquired immune deficiency syndrome or hiv infection
3) Confidence 0.03 Published 2010 Journal AIDS Res Ther Section Body Doc Link PMC3018377 Disease Relevance 0.61 Pain Relevance 0

General Comments

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