INT271904

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tsc2) signal transduction (Tsc2) Golgi apparatus (Tsc2)
nucleus (Tsc2) protein complex (Tsc2) cytoplasm (Tsc2)
Anatomy Link Frequency
kidney cortex 1
Tsc2 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 3 5.00 Very Low Very Low Very Low
transdermal 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 9 89.88 High High
Tuberous Sclerosis 33 88.80 High High
Stress 6 84.32 Quite High
Cancer 60 79.92 Quite High
Disease 63 75.80 Quite High
Sprains And Strains 9 63.52 Quite High
Renal Cancer 9 53.20 Quite High
Papillomavirus Infection 3 46.72 Quite Low
Syndrome 6 20.80 Low Low
Polycystic Kidney Disease 18 14.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Akt-mediated phosphorylation of tuberin has been demonstrated to regulate both, the translocation of tuberin from the membrane to cytosol and the nuclear/cytoplasmic localisation of tuberin [44].


Localization (translocation) of tuberin
1) Confidence 0.41 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.32 Pain Relevance 0
OGG1 localizes with tuberin preferentially in kidney cortex.
Localization (localizes) of tuberin in kidney cortex
2) Confidence 0.33 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.67 Pain Relevance 0
Akt-mediated phosphorylation of tuberin has been demonstrated to regulate both, the translocation of tuberin from the membrane to cytosol and the nuclear/cytoplasmic localisation of tuberin [44].


Localization (localisation) of tuberin
3) Confidence 0.33 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.32 Pain Relevance 0

General Comments

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