INT271935

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Rps6) structural constituent of ribosome (Rps6) ribosome (Rps6)
nucleolus (Rps6) nucleus (Rps6) cytoplasm (Rps6)
Rps6 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 1 5.00 Very Low Very Low Very Low
transdermal 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hamartoma 8 58.00 Quite High
Death 4 56.60 Quite High
Apoptosis 3 52.44 Quite High
Tuberous Sclerosis 11 50.00 Quite Low
Cancer 20 27.60 Quite Low
Disease 21 5.00 Very Low Very Low Very Low
Angiomyolipoma 12 5.00 Very Low Very Low Very Low
Lymphangioleiomyomatosis 11 5.00 Very Low Very Low Very Low
Convulsion 9 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of the GAP function of TSC2 shifts the balance of its substrate Rheb to the Rheb-GTP form, which activates the mTOR protein and ultimately leads to phosphorylation of ribosomal protein S6 and 4E-BP1 resulting in increased protein synthesis and cell proliferation.
Positive_regulation (leads) of Phosphorylation (phosphorylation) of ribosomal protein S6
1) Confidence 0.02 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.17 Pain Relevance 0

General Comments

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