INT271940

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.70
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Tsc2) signal transduction (Tsc2) Golgi apparatus (Tsc2)
nucleus (Tsc2) protein complex (Tsc2) cytoplasm (Tsc2)
Tsc2 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 2 5.00 Very Low Very Low Very Low
transdermal 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Papillomavirus Infection 2 98.80 Very High Very High Very High
Cancer 40 82.72 Quite High
Syndrome 4 78.76 Quite High
Polycystic Kidney Disease 12 72.16 Quite High
Disease 42 59.68 Quite High
Tuberous Sclerosis 22 50.00 Quite Low
Angiomyolipoma 24 5.00 Very Low Very Low Very Low
Lymphangioleiomyomatosis 22 5.00 Very Low Very Low Very Low
Convulsion 18 5.00 Very Low Very Low Very Low
Hamartoma 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Proteasome-mediated degradation of tuberin has been shown to be induced via its binding to the E6 oncoprotein of the human papillomavirus (HPV16 E6).
Protein_catabolism (degradation) of tuberin associated with papillomavirus infection
1) Confidence 0.50 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.32 Pain Relevance 0
HPV16 E6-induced degradation of tuberin leads to activation of S6K [39].
Protein_catabolism (degradation) of tuberin
2) Confidence 0.50 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.38 Pain Relevance 0

General Comments

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