INT272010

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tsc2, OGG1) nucleus (Tsc2, OGG1) nucleoplasm (OGG1)
mitochondrion (OGG1) lyase activity (OGG1) Golgi apparatus (Tsc2)
Tsc2 (Mus musculus)
OGG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 1 5.00 Very Low Very Low Very Low
transdermal 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 3 99.96 Very High Very High Very High
Stress 2 94.40 High High
Cancer 20 90.00 High High
Tuberous Sclerosis 11 73.12 Quite High
Sprains And Strains 3 47.84 Quite Low
Renal Cancer 3 37.52 Quite Low
Disease 21 28.72 Quite Low
Angiomyolipoma 12 5.00 Very Low Very Low Very Low
Lymphangioleiomyomatosis 11 5.00 Very Low Very Low Very Low
Convulsion 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tuberin downregulates the DNA repair enzyme 8-oxoguanine DNA-glycosylase (OGG1) with important functional consequences, compromising the ability of cells to repair damaged DNA resulting in the accumulation of the mutagenic oxidized DNA, 8-oxo-dG.
Tuberin Negative_regulation (downregulates) of OGG1
1) Confidence 0.17 Published 2008 Journal Current Genomics Section Body Doc Link PMC2691673 Disease Relevance 0.60 Pain Relevance 0

General Comments

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