INT272039

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ddc, Aanat) lyase activity (Ddc) transferase activity, transferring acyl groups (Aanat)
cellular amino acid metabolic process (Ddc)
Ddc (Mus musculus)
Aanat (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 45 100.00 Very High Very High Very High
Dopamine 19 99.80 Very High Very High Very High
cocaine 85 97.00 Very High Very High Very High
Neurotransmitter 9 95.08 Very High Very High Very High
Glutamate 2 92.76 High High
monoamine 8 83.24 Quite High
gABA 1 77.68 Quite High
Eae 6 26.00 Quite Low
addiction 7 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Helminth Infection 28 75.12 Quite High
Drug Dependence 6 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Paralysis 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Nicotine Addiction 1 5.00 Very Low Very Low Very Low
Poisoning 1 5.00 Very Low Very Low Very Low
Alcohol Addiction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These include bas-1 (which encodes an aromatic amino acid decarboxylase (AADC) required for the production of serotonin and dopamine) [27], tdc-1 (which encodes an aromatic-L-amino-acid/L-histidine decarboxylase required for making tyramine and octopamine) [26], and eat-4 (which encodes a vesicular glutamate transporter important for glutamate-mediated neurotransmission) [28].
AADC Positive_regulation (required) of Gene_expression (production) of serotonin associated with glutamate, dopamine and serotonin
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2691951 Disease Relevance 0.26 Pain Relevance 0.87

General Comments

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