INT27207

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Context Info
Confidence 0.73
First Reported 1981
Last Reported 2010
Negated 4
Speculated 0
Reported most in Body
Documents 31
Total Number 34
Disease Relevance 15.44
Pain Relevance 2.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Psd) intracellular (Psd) cytoplasm (Psd)
Anatomy Link Frequency
spinal cord 1
brain 1
internal 1
edge 1
thoracic aorta 1
Psd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 180 100.00 Very High Very High Very High
Spinal cord 7 99.98 Very High Very High Very High
withdrawal 6 98.20 Very High Very High Very High
GABAergic 174 98.16 Very High Very High Very High
Hippocampus 39 98.08 Very High Very High Very High
long-term potentiation 55 96.72 Very High Very High Very High
Angina 2 96.56 Very High Very High Very High
Thoracotomy 2 95.68 Very High Very High Very High
Eae 7 94.32 High High
anesthesia 28 94.20 High High
Disease Link Frequency Relevance Heat
Dementia 218 100.00 Very High Very High Very High
Depression 206 100.00 Very High Very High Very High
Primary Sclerosing Cholangitis 127 100.00 Very High Very High Very High
Myocardial Infarction 6 100.00 Very High Very High Very High
Stroke 306 99.96 Very High Very High Very High
Aids-related Complex 378 99.88 Very High Very High Very High
Stress 24 99.70 Very High Very High Very High
Obesity 42 99.60 Very High Very High Very High
Coronary Artery Disease 14 99.10 Very High Very High Very High
Carotid Stenosis 22 97.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, as shown in the Table 1, there is a large variability of diagnostic tools used for the detection of PSD.
Gene_expression (detection) of PSD associated with depression
1) Confidence 0.73 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2515899 Disease Relevance 0.95 Pain Relevance 0.34
Although severe coronary artery disease was the most common underlying abnormality, PSD may be an expression of multiple causes.
Gene_expression (expression) of PSD in coronary artery associated with coronary artery disease and myocardial infarction
2) Confidence 0.67 Published 1981 Journal Arch. Intern. Med. Section Abstract Doc Link 7259375 Disease Relevance 1.47 Pain Relevance 0.19
Moreover, data from a more recent trial showed that sertraline treatment, 50 mg/day, had no advantage in comparison to placebo in preventing PSD (Almeida et al 2006).
Neg (preventing) Gene_expression (preventing) of PSD associated with depression
3) Confidence 0.55 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2515899 Disease Relevance 0.74 Pain Relevance 0.48
recently reported coordinate expression of BDNF, Zif268, PSD-95, and pCaMKII in
Gene_expression (expression) of PSD
4) Confidence 0.47 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.22 Pain Relevance 0.09
recently reported coordinate expression of BDNF, Zif268, PSD-95, and pCaMKII in
Gene_expression (expression) of PSD
5) Confidence 0.41 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.22 Pain Relevance 0.09
In addition to Arc, the PSD proteins PSD-95 and ?
Gene_expression (proteins) of PSD associated with aids-related complex
6) Confidence 0.41 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.51 Pain Relevance 0.09
PSD was produced by placing a split nylon ring around the thoracic aorta of the rabbits at a level of T6-7 during a sterile thoracotomy done under pentobarbital anesthesia.
Gene_expression (produced) of PSD in thoracic aorta associated with anesthesia and thoracotomy
7) Confidence 0.39 Published 1989 Journal Circ. Res. Section Abstract Doc Link 2582599 Disease Relevance 0 Pain Relevance 0.14
In a subsequent hospitalized cohort studied three months after stroke, PSD was found in 26% (66/251).33 The identified lower frequency of PSD in this study may be related to exclusion of patients with persistent aphasia, patients with persistent disturbed consciousness, recurrent stroke, age >75 years, and the uses of DSM–VI as well as CASI and MMSE in the diagnosis of PSD.
Gene_expression (found) of PSD associated with dementia, stroke and aphasia
8) Confidence 0.37 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695209 Disease Relevance 1.95 Pain Relevance 0.04
In addition to Arc, the PSD proteins PSD-95 and ?
Gene_expression (proteins) of PSD associated with aids-related complex
9) Confidence 0.36 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.51 Pain Relevance 0.09
-CaMKII, and PSD-95, three
Gene_expression (three) of PSD
10) Confidence 0.36 Published 2008 Journal Neural Plasticity Section Body Doc Link PMC2631155 Disease Relevance 0.82 Pain Relevance 0
The rats injected intrathecally with PSD-93/chapsin-110 antisense oligodeoxynucleotide every 24 h for 4 days displayed not only a remarkable decrease in spinal cord PSD-93/chapsin-110 expression but also a significant reduction in the paw withdrawal responses to thermal and mechanical stimuli during complete Freund's adjuvant-induced inflammatory pain and peripheral nerve injury-induced neuropathic pain.
Gene_expression (expression) of PSD-93 in spinal cord associated with nervous system injury, eae, neuropathic pain, withdrawal, peripheral nerve injury and spinal cord
11) Confidence 0.34 Published 2003 Journal Pain Section Abstract Doc Link 14581127 Disease Relevance 0.50 Pain Relevance 0.66
The number of Fos-labeled cells was significantly larger in PSR than in PSC and PSD conditions in 11 structures, namely the rostral zona incerta (rZI), the dorsomedial hypothalamic nucleus (DM), the medial tuberal nucleus (MTu), the tuberal part of the lateral hypothalamic area (tLH), the perifornical nucleus (PeF), the tuber cinereum (TC), the posterior hypothalamic area (PH), the VMH, the Arc, the ventral part of the premammillary nucleus (PMV) and the supramammillary nucleus (SuM).
Gene_expression (conditions) of PSD in zona incerta associated with aids-related complex and primary sclerosing cholangitis
12) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909908 Disease Relevance 0.92 Pain Relevance 0
At onset SSS (p = 0.019) and BI scores (p = 0.026) were worse in PSD.
Gene_expression (worse) of PSD associated with dementia
13) Confidence 0.32 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695209 Disease Relevance 1.97 Pain Relevance 0.08
Defining 0 nm as the edge of the PSD, this histogram shows that ?
Gene_expression (edge) of PSD in edge
14) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2901346 Disease Relevance 0 Pain Relevance 0.09
The major finding of the present study was the reduction in adiponectin retroperitoneal adipose tissue gene expression in PSD rats when compared to control rats, not accompanied by alterations in epididymal adipose tissue for adiponectin and TNF-?
Gene_expression (rats) of PSD in adipose tissue associated with obesity
15) Confidence 0.31 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2613381 Disease Relevance 0.47 Pain Relevance 0.14
The results maybe explain why the serum adiponectin did not have the same reduction of gene expression in PSD rats, and suggest that more time would be necessary for changings in dynamic variation of cortisol rather to provoke direct action in serum adiponectin.
Gene_expression (expression) of PSD
16) Confidence 0.31 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2613381 Disease Relevance 0.34 Pain Relevance 0
The pattern differed from the steeply rising expression of PSD-95 and GKAP during postnatal development (Figure 2A, B).
Gene_expression (expression) of PSD
17) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844417 Disease Relevance 0 Pain Relevance 0
These changes were well correlated with degree of dilatation and ratio of internal radius to wall thickness (hence, mean wall stress) but not with duration of PSD.
Gene_expression (duration) of PSD in internal associated with stress
18) Confidence 0.30 Published 1989 Journal Circ. Res. Section Abstract Doc Link 2582599 Disease Relevance 0.10 Pain Relevance 0.10
Overall, 3116 (2402 ; 4420), 1311 (1192; 1483) and 399 (193; 605) Fos-labeled neurons were counted in the tuberal and mammillary hypothalamus in PSR, PSD and PSC animals, respectively.
Gene_expression (animals) of PSD in neurons associated with primary sclerosing cholangitis
19) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909908 Disease Relevance 0.67 Pain Relevance 0
Thirteen structures contained more Fos-labeled cells in PSD than PSC animals.
Gene_expression (contained) of PSD associated with primary sclerosing cholangitis
20) Confidence 0.29 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909908 Disease Relevance 0.85 Pain Relevance 0

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