INT272146

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.38
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.28
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (IL8) signal transducer activity (PTAFR) extracellular space (IL8)
signal transduction (IL8) extracellular region (IL8) nucleolus (PTAFR)
Anatomy Link Frequency
epithelial cells 2
PTAFR (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 51 100.00 Very High Very High Very High
Potency 50 96.08 Very High Very High Very High
antagonist 38 88.88 High High
Inflammation 24 69.96 Quite High
agonist 10 39.52 Quite Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
bradykinin 2 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neonatal Necrotizing Enterocolitis 34 87.44 High High
INFLAMMATION 26 69.96 Quite High
Colon Cancer 1 52.64 Quite High
Hypersensitivity 16 25.00 Low Low
Death 4 7.52 Low Low
Edema 10 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Ocular Hypertension 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a time-dependent manner, PAF significantly increased the release of IL-6 and IL-8.
PAF Positive_regulation (increased) of Localization (release) of IL-8
1) Confidence 0.38 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2693427 Disease Relevance 0 Pain Relevance 0.12
PAF (10 nM–1 µM) stimulated the release of the proinflammatory cytokines, IL-6, IL-8, and GM-CSF, 1.4–3.5 fold above basal levels.
PAF Positive_regulation (stimulated) of Localization (release) of IL-8 associated with cytokine
2) Confidence 0.29 Published 2009 Journal Molecular Vision Section Abstract Doc Link PMC2693427 Disease Relevance 0 Pain Relevance 0.40
Platelet-activating factor induces TLR4 mRNA expression and promotes IL-8 secretion in intestinal epithelial cells
Platelet-activating factor Positive_regulation (promotes) of Localization (secretion) of IL-8 in epithelial cells
3) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2955554 Disease Relevance 0.28 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox