INT272205

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.08
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
muscle 2
limb 1
LGMD2I (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 240 83.12 Quite High
Inflammation 20 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscular Dystrophy 91 100.00 Very High Very High Very High
Disease 48 98.84 Very High Very High Very High
Sarcoglycanopathies 10 87.60 High High
Muscle Disease 102 82.44 Quite High
Hypertrophy 9 71.32 Quite High
Frailty 24 5.00 Very Low Very Low Very Low
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Neuromuscular Disease 14 5.00 Very Low Very Low Very Low
Oculopharyngeal Muscular Dystrophy 10 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mutations of CAPN3 in Korean Patients with Limb-Girdle Muscular Dystrophy

The limb-girdle muscular dystrophy type 2A (LGMD2A) is a recessively inherited disease caused by a mutation of the calpain 3 gene (CAPN3), and is considered one of the most prevalent subtypes of limb-girdle muscular dystrophy (LGMD).

Positive_regulation (girdle) of LGMD2A in limb associated with muscular dystrophy and disease
1) Confidence 0.12 Published 2007 Journal Journal of Korean Medical Science Section Title Doc Link PMC2693639 Disease Relevance 0.57 Pain Relevance 0
This distinct pattern is different from muscle involvement in LGMD2I and LGMD2A patients in which dystrophic changes in the posterior thigh and posterior calf muscle can frequently be observed [40].


Positive_regulation (involvement) of LGMD2I in muscle
2) Confidence 0.06 Published 2010 Journal Eur Radiol Section Body Doc Link PMC2940021 Disease Relevance 0.75 Pain Relevance 0.04
This distinct pattern is different from muscle involvement in LGMD2I and LGMD2A patients in which dystrophic changes in the posterior thigh and posterior calf muscle can frequently be observed [40].


Positive_regulation (involvement) of LGMD2A in muscle
3) Confidence 0.06 Published 2010 Journal Eur Radiol Section Body Doc Link PMC2940021 Disease Relevance 0.76 Pain Relevance 0.04

General Comments

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