INT272274

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Context Info
Confidence 0.60
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 24
Total Number 24
Disease Relevance 27.55
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
outflow 1
blood 1
eyes 1
anterior chamber 1
NARFL (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 23 98.54 Very High Very High Very High
cva 13 90.00 High High
Potency 2 89.04 High High
agonist 32 86.52 High High
dexamethasone 6 84.92 Quite High
beta blocker 23 84.56 Quite High
eye pain 6 75.72 Quite High
ischemia 19 73.48 Quite High
Fibrositis 1 53.00 Quite High
rheumatoid arthritis 2 52.44 Quite High
Disease Link Frequency Relevance Heat
Ocular Hypertension 2053 100.00 Very High Very High Very High
Postoperative Complications 5 99.60 Very High Very High Very High
Glaucoma 620 99.32 Very High Very High Very High
Hypotension 60 99.30 Very High Very High Very High
Syndrome 19 99.30 Very High Very High Very High
Diabetes Mellitus 47 98.56 Very High Very High Very High
Pain 23 98.54 Very High Very High Very High
Open-angle Glaucoma 25 98.30 Very High Very High Very High
Hyphema 16 97.44 Very High Very High Very High
Eye Disease 17 96.96 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 40 eyes (27.2%), topical treatment was initiated to reduce the IOP when persistent elevation above 25 mm Hg was observed over one month in weekly examinations after the first observation of IOP ?
Localization (observation) of IOP in eyes associated with ocular hypertension
1) Confidence 0.60 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2698684 Disease Relevance 1.37 Pain Relevance 0
The high dosage used by Jonas (2005) was associated with a higher rate of IOP increase lasting up to 9 months longer than observed for the 4 mg dose.
Localization (increase) of IOP associated with ocular hypertension
2) Confidence 0.60 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2698684 Disease Relevance 1.22 Pain Relevance 0
Despite the latter, the benefit of IVTA injections should be meticulously weighed in glaucoma patients against the risk of significant IOP increase.
Localization (increase) of IOP associated with glaucoma and ocular hypertension
3) Confidence 0.46 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693970 Disease Relevance 1.52 Pain Relevance 0.04
Table 1 shows the distribution of IOP at different time segments.
Localization (distribution) of IOP associated with ocular hypertension
4) Confidence 0.44 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693970 Disease Relevance 1.35 Pain Relevance 0
A similar pattern of IOP rise was reported in several other studies (Wingate et al 1999; Jonas et al 2003c; Massin et al 2004; Smithen et al 2004).
Localization (rise) of IOP associated with ocular hypertension
5) Confidence 0.44 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693970 Disease Relevance 1.32 Pain Relevance 0
The IOP measured two minutes post eyedrop instillation was not significantly different from the IOP measured after five minutes (p > 0.05).
Localization (measured) of IOP associated with ocular hypertension
6) Confidence 0.41 Published 2007 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2701119 Disease Relevance 1.21 Pain Relevance 0
The IOP was lowered to 16 mmHg by anterior chamber paracentesis, but a 1.5-mm high hyphema developed.
Localization (lowered) of IOP in anterior chamber associated with hyphema and ocular hypertension
7) Confidence 0.32 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2908824 Disease Relevance 1.40 Pain Relevance 0.34
Since the IOP elevation and pain usually happened in the afternoon following hemodialysis, we decided to check his IOP both before and after the hemodialysis.
Localization (check) of IOP associated with pain and ocular hypertension
8) Confidence 0.32 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2908824 Disease Relevance 1.64 Pain Relevance 0.34
In a Swiss survey by Gugleta, increased compliance and subjective convenience were suggested reasons for the average IOP decrease of 1.5 mmHg upon switch from dorzolamide and timolol to the combination therapy and high continuation rate on the combination therapy (Gugleta et al 2003).
Localization (decrease) of IOP associated with ocular hypertension
9) Confidence 0.27 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693974 Disease Relevance 0.41 Pain Relevance 0
The results showed that the combination of brimonidine and latanoprost produced greater mean IOP reductions at each visit in both trials (Zabriskie and Netland 2003).


Localization (reductions) of IOP associated with ocular hypertension
10) Confidence 0.27 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693974 Disease Relevance 0.78 Pain Relevance 0.12
IOP elevation by OVDs
Localization (elevation) of IOP associated with ocular hypertension
11) Confidence 0.25 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2698691 Disease Relevance 0.84 Pain Relevance 0
A family history of glaucoma should be elicited in all patients, as this may be a predisposition to higher IOP rise following IVTA.
Localization (rise) of IOP associated with glaucoma and ocular hypertension
12) Confidence 0.16 Published 2008 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2694598 Disease Relevance 1.10 Pain Relevance 0.03
Other parameters such as gender did not show a marked influence on frequency and amount of elevation of IOP.
Localization (elevation) of IOP associated with ocular hypertension
13) Confidence 0.16 Published 2008 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2694598 Disease Relevance 1.09 Pain Relevance 0
Patients with OH or OAG were washed out of their usual ocular hypotensive medications and then those with a baseline IOP ?
Localization (baseline) of IOP associated with hypotension, open-angle glaucoma and ocular hypertension
14) Confidence 0.16 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2993108 Disease Relevance 1.26 Pain Relevance 0.04
This suggests that steroid-induced glaucoma may be hereditary or a family history of glaucoma may predispose someone to higher IOP rise following IVTA.
Localization (rise) of IOP associated with glaucoma and ocular hypertension
15) Confidence 0.15 Published 2008 Journal The Open Ophthalmology Journal Section Body Doc Link PMC2694598 Disease Relevance 1.08 Pain Relevance 0.04
Evaluation of Ehlers IOP and PASCAL IOP
Localization (Evaluation) of PASCAL IOP associated with ocular hypertension
16) Confidence 0.11 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2909890 Disease Relevance 1.94 Pain Relevance 0
Evaluation of Ehlers IOP and PASCAL IOP
Localization (Evaluation) of IOP associated with ocular hypertension
17) Confidence 0.11 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2909890 Disease Relevance 1.93 Pain Relevance 0
A patient with vasospastic syndrome may not be able to compensate for elevations of IOP and/or blood pressure dips, while a healthy patient can autoregulate to maintain consistent ocular perfusion.
Localization (elevations) of IOP in blood associated with syndrome and ocular hypertension
18) Confidence 0.11 Published 2008 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2699797 Disease Relevance 1.76 Pain Relevance 0.12
Thus, the factors able to affect IOP are: (i) rate of aqueous humor secretion; (ii) resistance encountered in outflow channels; (iii) pressure at the level of the episcleral venous.
Localization (secretion) of IOP in outflow associated with ocular hypertension
19) Confidence 0.10 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2701282 Disease Relevance 0.63 Pain Relevance 0
20% IOP decrease was higher with bimatoprost than with latanoprost, and more bimatoprost patients achieved a lower pressure range (Noecker et al 2003).
Localization (decrease) of IOP associated with ocular hypertension
20) Confidence 0.10 Published 2007 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2701126 Disease Relevance 1.15 Pain Relevance 0.03

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