INT272275

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 1
Speculated 2
Reported most in Body
Documents 8
Total Number 12
Disease Relevance 16.68
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
eyes 6
medial 2
NARFL (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 32 100.00 Very High Very High Very High
Inflammation 88 98.82 Very High Very High Very High
fibrosis 13 98.36 Very High Very High Very High
headache 8 74.48 Quite High
ischemia 50 64.08 Quite High
eye pain 4 42.00 Quite Low
Calcium channel 9 5.00 Very Low Very Low Very Low
Rheumatism 8 5.00 Very Low Very Low Very Low
cva 7 5.00 Very Low Very Low Very Low
corticosteroid 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 669 100.00 Very High Very High Very High
Pain 32 100.00 Very High Very High Very High
Disease Progression 7 100.00 Very High Very High Very High
Glaucoma 357 99.66 Very High Very High Very High
Shock 8 98.92 Very High Very High Very High
INFLAMMATION 90 98.82 Very High Very High Very High
Blister 13 98.68 Very High Very High Very High
Fibrosis 13 98.36 Very High Very High Very High
Disease 46 95.28 Very High Very High Very High
Uveitis 9 95.12 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The significant increase in IOP levels observed in the first hour in our cases was probably due to the volume-effect of the injected IVTA; only 8.8% of the eyes showed a moderately elevated IOP in the first hour postinjection.
Regulation (effect) of Positive_regulation (increase) of IOP in eyes associated with ocular hypertension
1) Confidence 0.36 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2698684 Disease Relevance 1.36 Pain Relevance 0
This was because intradialytic IOP elevations were controlled before the formation of the fibrous membrane.
Regulation (controlled) of Positive_regulation (elevations) of IOP associated with ocular hypertension
2) Confidence 0.26 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2908824 Disease Relevance 1.76 Pain Relevance 0.14
Masuda et al.7 reported that Argon laser trabeculoplasty successfully controlled the IOP elevation in exfoliative glaucoma patients showing intradialytic IOP elevation, while Choong et al.6 reported that bilateral IOP elevation after hemodialysis stabilized with topical ?
Regulation (controlled) of Positive_regulation (elevation) of IOP associated with glaucoma and ocular hypertension
3) Confidence 0.26 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2908824 Disease Relevance 1.42 Pain Relevance 0.07
In this subgroup, anti-glaucoma therapy was given to control IOP increase at month 1 after the first IVTA injection in 3 eyes (IOP range: 28–42 mmHg), at month 3 after the first IVTA injection in 7 eyes (IOP range: 28–38 mmHg), and at month 6 after a second IVTA injection in 5 eyes (IOP range: 25–40 mmHg).
Regulation (control) of Positive_regulation (increase) of IOP in eyes associated with glaucoma and ocular hypertension
4) Confidence 0.17 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693970 Disease Relevance 1.61 Pain Relevance 0
There have been studies on Korean nonglaucomatous patients with IOP elevations during hemodialysis and also on the medial control of intradialytic IOP elevation in Korean nonglaucomatous patients; but reports on glaucoma patients have been limited.
Regulation (control) of Positive_regulation (elevation) of IOP in medial associated with glaucoma and ocular hypertension
5) Confidence 0.12 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2908824 Disease Relevance 1.50 Pain Relevance 0.07
Further treatments with intravenous mannitol, oral carbonic anhydrase inhibitor, topical antiglaumatic agents and subconjunctival 5-fluorouracil (5-FU) injections all failed to control relapsing pain and IOP elevation.
Neg (failed) Regulation (control) of Positive_regulation (elevation) of IOP associated with pain and ocular hypertension
6) Confidence 0.12 Published 2006 Journal Korean Journal of Ophthalmology : KJO Section Abstract Doc Link PMC2908824 Disease Relevance 1.21 Pain Relevance 0.18
Molecular characteristic of OVDs should have significant effects on the likelihood of IOP elevation.
Regulation (effects) of Positive_regulation (elevation) of IOP associated with ocular hypertension
7) Confidence 0.09 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2698691 Disease Relevance 1.14 Pain Relevance 0
Other glaucoma risk factors that may be responsible for disease progression despite lowering of IOP include vascular risk factors, genetics, and other systemic conditions (Leske 2007).
Spec (may) Regulation (responsible) of Positive_regulation (lowering) of IOP associated with glaucoma, ocular hypertension and disease progression
8) Confidence 0.06 Published 2008 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2699797 Disease Relevance 2.20 Pain Relevance 0
Our study showed that both the APACG group and the CPACG group had significantly higher IOP levels and corresponding significantly higher flare value and cell counts than the healthy control group, implying that IOP elevation might be responsible for the changes of the BAB in the two PACG groups.
Spec (might) Regulation (responsible) of Positive_regulation (elevation) of IOP associated with glaucoma and ocular hypertension
9) Confidence 0.06 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965576 Disease Relevance 1.48 Pain Relevance 0.14
The effect of IOP elevation on the BAB was accessed by comparing flare value and cell counts of the two PACG groups to those of the age-matched healthy control group.
Regulation (effect) of Positive_regulation (elevation) of IOP associated with glaucoma and ocular hypertension
10) Confidence 0.05 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965576 Disease Relevance 1.16 Pain Relevance 0.06
In this study, we used laser flare cell photometry for aqueous flare and cells measurements to both quantitatively evaluate the inflammation in the anterior chamber in eyes with PACG and explore the influence of IOP elevation on the BAB.


Regulation (influence) of Positive_regulation (elevation) of IOP in eyes associated with inflammation, glaucoma and ocular hypertension
11) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965576 Disease Relevance 0.89 Pain Relevance 0.08
However, the effect of IOP elevation as a potential mechanical shock on the BAB has not been studied until the present.
Regulation (effect) of Positive_regulation (elevation) of IOP associated with shock and ocular hypertension
12) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965576 Disease Relevance 0.94 Pain Relevance 0.12

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