INT272290

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.25
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP4B1) endoplasmic reticulum (CYP4B1)
CYP4B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 53 99.52 Very High Very High Very High
cINOD 80 98.38 Very High Very High Very High
Inflammatory response 2 83.76 Quite High
aspirin 2 83.12 Quite High
corticosteroid 9 75.04 Quite High
COX2 11 60.96 Quite High
cOX1 9 42.40 Quite Low
Potency 4 18.92 Low Low
diclofenac 13 7.84 Low Low
acular 24 6.88 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 56 99.52 Very High Very High Very High
Injury 11 81.28 Quite High
Hypoxia 6 80.32 Quite High
Ocular & Orbital Inflammation 3 73.48 Quite High
Disease 3 57.76 Quite High
Cataract 18 37.12 Quite Low
Toxicity 13 25.28 Quite Low
Pain 14 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 5 5.00 Very Low Very Low Very Low
Hemorrhage 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NSAIDs may also potentiate peroximase proliferator-activated receptors with subsequent induction of CYP4B1 activity and production of the pro-inflammatory compounds 12-HETE and 12-HETrE.
Positive_regulation (induction) of Gene_expression (production) of CYP4B1 associated with inflammation and cinod
1) Confidence 0.24 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693998 Disease Relevance 1.25 Pain Relevance 1.01

General Comments

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